Üner, Oğul Ersin (2013) The Investigation of the Effect of the Concentration of Rhus verniciflua Herb on the Cell Viability of Homo sapiens Liver Cancer Cells. Other thesis, TED ANKARA COLLEGE FOUNDATION PRIVATE HIGH SCHOOL.
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Abstract
Our lives are based on cells, the functional basic unit of organisms.1 Our cells constantly divide, and sometimes they divide in an abnormal pattern, which is called cancer. Although some drugs are used to treat cancer, scientists think that using anticancerogenous herbs can also be effective in alleviating the disease. The focus of this study is to test the effect of concentration of an anticancerogenous herb on the viability of cancer cells. It is very difficult to test all of the anticancerogenous herbs and cancer cells, so Rhus verniciflua (sumac herb) and human (Homo sapiens) hepatocellular carcinoma liver cancer cells are tested. So the aim of this study is to investigate whether the concentration of the Rhus verniciflua herb has an effect on the liver cancer cells by measuring cell viability values after giving cells the herb in different concentrations. In the experiment, the herbs were liquefied and given to liver cancer cells via serial dilution and those were then installed into the microplate reader for determining the absorption values. These values were then processed and percent cell viability results were obtained. As the concentration of the herb drug increases, the absorption values, thus the cell viability results decreases. In this investigation, it was found that increased concentrations of the sumac solution have an effect on the liver cancer cells. The least cell viability is observed in the 20 μM sumac solution and the most cell viability is observed in 1.2 μM sumac solution. Overall, the results of this study advocates the hypothesis that concentration of sumac solution affects the cell viability of hepatocellular carcinoma liver cancer cells and the optimum dosage of the drug is 2.0 μM, which would result in maximum potency.
| Item Type: | Thesis (Other) |
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| Additional Information: | Supervisor: Mrs. Didem Oluklulu, IB Notu: B |
| Uncontrolled Keywords: | sumac solution, cancer cells, Rhus verniciflua, Cell Viability |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Depositing User: | Users 114 not found. |
| Date Deposited: | 18 Sep 2013 06:37 |
| Last Modified: | 18 Sep 2013 06:37 |
| URI: | http://tedprints.tedankara.k12.tr/id/eprint/388 |
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